[Item: Lum Berry] [EVs: 252 HP / 4 Def OR Sp.Def /252 Speed] [Nature: Timid (+Speed -Attack)]
Switch Lyrica in, predict whether the enemy will try a special or physical attack, then set up the screens appropriately. E.g you will put up Reflect before Light Screen against Meiling, but Light Screen before Reflect against Sanae. When you're done, if you are still surviving, choose any of the moves below. Safeguard and Taunt are decent if you plan to send in a sweeper in order to prevent any form of status. Perish Song is abusively good ingame because the AI does not switch their pokemon out before they die. It is very slow though, so only use it if you plan to send out a bulky touhoumon who can take their time setting up (Mana Charge Kaguya, for example). Screech is good if you plan to send in a physical attacker. Memento is a 220 power Dark-type move that KOs Lyrica, you can use it against enemies weak to Dark.
Lum Berry is suggested on this set, as you do not want to be paralyzed, frozen or put to sleep while setting up.